It has been recently found out that a common drug which is used cure high levels of blood pressure may also be used in treating the lethal disease of multiple sclerosis.
A recent study throws light on the fact that a common and an economical drug used for optimizing high blood pressure called lisinopril has helped tremendously and been fruitful in blocking the growth of multiple sclerosis of the mice that are subjects in the laboratory. The mice were made to consume the drug as they had matured and all the symptoms of multiple sclerosis. This helped in transforming their paralysis without harming their immunity of the body.
Multiple Sclerosis (MS) is a painful and a deadly disease that has a detrimental effect on the body’s resistant system. This results in the malfunctioning of the immune system of the body. This disease may ultimately lead to paralysis or death of the patient. One of the biggest drawbacks is that the disease is complex and curing it means that the body’s immune system will be affected adversely.
Blood Pressure Drug – Lisinopril
According to researcher Lawrence Steinman, MD, Stanford University, states that the ailment of multiple sclerosis and high levels of blood pressure both include inflammatory process that may be advantageous if cured by the drug – lisinopril. If the research concludes the same then the medicinal value of the drug will surely be a great and an economical way of curing the nasty ailment.
This research was mentioned in the journal Proceedings of the National Academy of Sciences. It was thoroughly researched and the after effects of the drug that was consumed by the mice led to the manifestation and growth of brain lesions that is common in people suffering from MS after they are treated with chemical doses.
The Experiment
The team of researchers gave the mice equal portions of the drug – lisinopril that is given to control high levels of blood pressure prior and after the injection causing the disease.
The conclusion was the mice that had consumed the dose before the injection had no shown no signs of paralysis that is commonly linked to MS. The mice that were given the drug after the injection clearly displayed the signs of re-occurrence of paralysis.
The researchers were surprised to find that the cure with the drug had effectively diminished few of the soreness markers that are generally found during the occurrence of MS which affects the overall function of the immune system.
This research also triggered the fact that the drug manifested the creation of a significant number of immune cells that are termed as regulatory T cells that safeguard against any immune ailment.
According to Steinman this is bound to be a new and a challenging avenue for research which may result in path breaking achievements in treating MS.
He states that they were interesting and fascinating facts that have surfaced after this experiment or else it would have been another research paper that would told people what all could have been done in mice. He mentioned in the press conference that they are ready to curative calculation in MS caused in human beings.
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