Benefits Of Using Oral Contraceptives In Asthma Treatment For Premenstrual Women
Posted by Admin | Posted in Asthma, Health News | Posted on 25-11-2009
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As per the suggestions of early research, treatment using oral contraceptives can help premenopausal in treating asthma though the symptoms of asthma are not associated with the menstrual cycles.
In a rigorous research conducted by at University of Alberta, the researchers have proved that varying levels of progesterone and estrogen can have straight effect on the markings of air duct inflammation. Oral contraceptives are used as supplementary treatments for women suffering from asthma whose symptoms are linked closely with their periods. The data to prove the influence of the sex hormones progesterone and estrogen on asthma was not available earlier and with this research proving it, new methods for treating asthma for pregnant women have evolved.
The research was conducted on seventeen premenopausal women who had moderate or severe asthma and were asked to meet the research crew everyday over the time span of 36 days till the entire menstrual cycle was complete. The measurement of levels of progesterone and estrogen were done each day and also the marking of air duct inflammation and asthma symptoms were supervised every day. Also, the skin-prick allergy tests were carried out every alternate day. The research required lot of efforts from every person involved and problems like university closure, snow storms and power outages were faced during it. But with much effort from everyone, 99 percent of the planned assessments were carried out with fail.
9 of the women in study were making use of oral contraceptives and 8 were not using them. Out of seventeen women, four had asthma symptoms associated with menstrual cycle. Since women who take oral contraceptives did not have noticeable modifications in the progestin and estrogen during their menstrual cycles, they did not anticipate any variations in the asthma throughout their menstrual cycle.
Women who do not take oral contraceptive must have changes in the levels of progesterone and estrogen which can cause some variations in the markers. The women who feel large variations in progesterone but minimal changes in estrogen during the menstrual cycle are most likely susceptible to asthma related cycle.
Mandhane hopes that the determinations prove the bigger studies examining the use of oral contraceptives for treatment with premenopausal women. The famous pain reliever acetaminophen has been associated with an enhanced risk of asthma in adults and children based on a new research review of the articles published earlier by Canadian researchers.
The research has successfully proved that throughout menstruation period, women who suffer from asthma and did not take oral contraceptives had smaller levels of breathed out Nitric Oxide (eNO) which is an indicator of air duct inflammation. Also, the women who do not use oral contraceptives had greater average eNo levels that the women who used oral contraceptives. Also, among the asthma infected women who did not use oral contraceptives, the estrogen levels were increased with the reduction in eNO, while the increase progesterone levels was mainly linked with the increase in levels of eNO. Scientists ponder that Oral contraceptives can have crucial role in managing asthma treatment in premenopausal women.