A Research – Are Heartburn Drugs all Rights with Plavix?
Posted by Admin | Posted in Health News, Heartburn/GERD | Posted on 12-01-2010
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The Heart patients taking the drug plavix can also take the PPI drug (proton pump inhibitor) for acid reduction safely as per the suggestion of 2 earlier researches. The new discovery seems to be contradictory with certain recent researches which shows negative results in heart patients taking plavix along with PPI particularly who take Prilosec drug.
In a very recent research, which was done in March, the patients of heart attack who were taking Plavix along with PPI were more prone to 2nd heart attack when compared to other patients who were taking Plavix without taking PPI. Plavix along with another drug Effient got its FDA approval in june and was suggested for patient with heart attack in combination with aspirin for avoiding blood clots which can cause stroke or 2nd attacks.
The Prisolic, Prevacid, Protnoix and Nexium etc. are PPIs which are offered to decrease risks of intestinal or stomach bleedings, caused by anti-clotting drugs.
PPIs all right along With Plavix
The new study did not show any increase in risk along with stroke, cardiovascular death or stroke among patients who took both Plavix and PPIs. They did not find any cardiovascular problems associated with people who used these drugs. There is a contradiction between current discoveries and previous analyzes.
One more point is that PPIs are often suggested to severe heart patients. The studies were patronized by Eli Lilly & Co, the manufacturers were Effient and compared with Plavix drug. The 2 trials involved more than thirteen thousand six hundred patients who suffered a heart attack previously and had unstable angina which were treated with the 2 drugs.
Patients who took the analysis were young and were less probable to suffer from kidney failure or diabetes while earlier trials involved many patients who showed bad results with usage of PPI. This explains why the patients using PPI show poor health when compared with many other patients involved in the research. 1/3 of the patients who participated in trial also took PPI, but it was not found linked with high risk of 2nd heart attack, fatal cardio vascular problem or stroke with any of the 2 anti-clotting medicines.
PPIs are not suitable for All
The research reports are scheduled to get published in an approaching publication of The Lancet journal. The present results offer some support to the practitioners that PPIs and Effient could be combined and used safely by patients who have been suggested to use them both. But PPIs must not be offered to all individuals who take Effient or Plavix.
In an editorial column that was issued along with research, it was written that usage of PPI might be particularly of high risk to a minor group of heart patients who are predisposed genetically to have low response to such anti-clotting medicines. Patients who take Effient or Plavix along with PPI should be looked after by their physicians carefully for any consequences.